Cheap Train Tickets From St Louis to Chicago Takes You to The Windy City

Cheapest dates for St Louis - Chicago train tickets

  • any
  • November 2026
  • December 2026
  • January 2027
  • February 2027
  • March 2027
  • April 2027
  • May 2027
  • June 2027
  • July 2027
  • August 2027
  • September 2027
  • October 2027
  • popularity
  • price
  • arrival city
$68
Amtrakoutward: Dec 6, 2026
direct (5h03m)
Amtrak
Amtrakinbound: Dec 8, 2026
direct (4h59m)
Amtrak
$79
Amtrakoutward: Dec 4, 2026
direct (5h03m)
Amtrak
Amtrakinbound: Dec 8, 2026
direct (4h59m)
Amtrak
$80
Amtrakoutward: Dec 4, 2026
direct (5h03m)
Amtrak
Amtrakinbound: Dec 8, 2026
direct (4h59m)
Amtrak
$80
Amtrakoutward: Dec 4, 2026
direct (5h03m)
Amtrak
Amtrakinbound: Dec 8, 2026
direct (4h59m)
Amtrak
$80
Amtrakoutward: Dec 4, 2026
direct (5h03m)
Amtrak
Amtrakinbound: Dec 8, 2026
direct (4h59m)
Amtrak
$97
Amtrakoutward: Nov 15, 2026
direct (5h03m)
Amtrak
Amtrakinbound: Nov 17, 2026
direct (4h59m)
Amtrak
$97
Amtrakoutward: Nov 15, 2026
direct (5h03m)
Amtrak
Amtrakinbound: Nov 17, 2026
direct (4h59m)
Amtrak
$97
Amtrakoutward: Nov 15, 2026
direct (5h03m)
Amtrak
Amtrakinbound: Nov 17, 2026
direct (4h59m)
Amtrak
$126
Amtrakoutward: Nov 20, 2026
direct (5h03m)
Amtrak
Amtrakinbound: Nov 23, 2026
direct (5h01m)
Amtrak
$129
Amtrakoutward: Nov 14, 2026
direct (5h03m)
Amtrak
Amtrakinbound: Nov 17, 2026
direct (4h59m)
Amtrak
$138
Amtrakoutward: Nov 12, 2026
direct (4h55m)
Amtrak
Amtrakinbound: Nov 15, 2026
direct (4h46m)
Amtrak
$138
Amtrakoutward: Nov 12, 2026
direct (4h55m)
Amtrak
Amtrakinbound: Nov 15, 2026
direct (4h46m)
Amtrak
$151
Amtrakoutward: Nov 19, 2026
direct (5h05m)
Amtrak
Amtrakinbound: Nov 24, 2026
direct (4h59m)
Amtrak
$151
Amtrakoutward: Nov 19, 2026
direct (5h05m)
Amtrak
Amtrakinbound: Nov 24, 2026
direct (4h59m)
Amtrak
$158
Amtrakoutward: Nov 20, 2026
direct (5h03m)
Amtrak
Amtrakinbound: Nov 24, 2026
direct (4h59m)
Amtrak
$251
Amtrakoutward: Nov 21, 2026
direct (5h05m)
Amtrak
Amtrakinbound: Nov 23, 2026
direct (4h46m)
Amtrak
Return
Departure

Travel guide St Louis–Chicago

Information

Enjoy more of the midwest by travelling via train! Chicago offers a magnitude of industrial history, urban culture and spectacular modern art, and it is just one railroad away.

What train companies operate the route from St. Louis to Chicago?

Amtrak operates the train route from St. Louis to Chicago.

What is the schedule for the train route from St. Louis to Chicago?

Trains begin their operation at 4:35 am and run until 5:30 pm, at various times, daily. You will be sure to find a train that will fit your particular schedule.

What are the departure and arrival train stations for the route from St. Louis to Chicago?

The journey begins at the St. Louis train station and ends at Union Station in Chicago.

What distance is the train route from St. Louis to Chicago?

Approximately 297.1 miles seperate St. Louis from Chicago.

How long does it take to travel from St. Louis to Chicago by train?

The travel time between St. Louis and Chicago is a little over five and a half hours.

What are the stops on the train route from St. Louis to Chicago?

There are no stops on this journey.

Why should you travel by train from St. Louis to Chicago?

First class accommodations, meal services, WiFi, and checked baggage come with Amtrak travel. Sit back relax, and enjoy the stress-free ability to traverse the Midwest.

What is there to see and do in Chicago?

The Windy City offers a variety of activities to delight any passenger. Baseball fans will enjoy the famous Millennium Park. Shedd Aquarium excites younger and older audiences alike. A plethora of art and natural museums can be conveniently found downtown.